Beneath the surface of your gut lies a vast network of neurons—as many as in your spinal cord. New research from the Champalimaud Foundation (CF) in Lisbon shows that in mice this "second brain" helps ...

Robert Burakoff, MD, MPH, is a board-certified gastroenterologist who serves as vice chair of Ambulatory Services at Lower Manhattan Hospital and professor of medicine at the Weill Cornell Medical ...

In a new study published in Cell Reports titled, “C9orf72 in myeloid cells prevents an inflammatory response to microbial glycogen,” researchers from Case Western Reserve University have identified a ...

A significant discovery by Case Western Reserve University researchers could change how doctors treat two of the most devastating neurodegenerative diseases. The team identified a link between gut ...

The effects of depression may infiltrate your very bones – and conversely, your bones may send penetrating messages all the way back to your brain. This two-way street is a captivating new field of ...

The gut-brain-vagal axis The vagus nerve is the main pathway of the gut-brain axis, a complex communication network linking peripheral organs to the brain by transmitting interoceptive signals about ...

People with Parkinson’s disease have α-synuclein clumps in the brain, but these aggregates are not the only thing clogging them up. Constipation plagues many PD patients, often decades before motor ...

Chronic stress can damage the gut’s protective lining, triggering inflammation that may worsen depression. New research shows that stress lowers levels of a protein called Reelin, which plays a key ...

Digestive symptoms often appear years before tremor in Parkinson’s disease, and growing evidence suggests the gut-brain axis may play a critical role in early disease processes and symptom management.

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The microorganisms in our gastrointestinal tract–the gut microbiome can exert a profound influence on the human body, and scientists are learning more about exactly how certain microbes can impact us.